A pump’s performance suddenly drops, ruining your process. Dried residue inside the pump head is causing clogs and permanent damage, forcing expensive, premature replacement.
Prompt cleaning is vital. It prevents dried residues from clogging valves, stops cross-contamination between fluids, and protects the diaphragm from chemical damage. This ensures consistent performance and maximizes the pump’s operational lifespan.

I’ve seen too many perfectly good pumps fail for one simple reason: neglect. An engineer calls in frustrated that their pump’s flow rate has collapsed, assuming a major mechanical failure. More often than not, the culprit is dried residue from the fluid they were pumping—inks, reagents, or buffers. A simple flushing procedure after each use could have prevented the entire problem. Understanding what happens inside the pump when liquids are left to dry is the key to avoiding these costly and frustrating failures.
What Happens When Liquid Dries Inside a Pump?
You finish a task and leave the pump idle. The harmless liquid left inside begins to evaporate, transforming into a hard, cement-like solid that can seize the pump’s internal components.
When a liquid sits, its volatile components (like water or solvents) evaporate. This leaves behind a concentrated, hardened mass of the dissolved solids—be it salt crystals, ink pigments, or chemical reagents—that is physically destructive.

The transformation from a free-flowing liquid to a damaging solid is the root cause of all subsequent problems. A pump’s internal passages and valve seats have extremely tight tolerances, and even a thin layer of hardened material can cause a total failure. This isn’t a slow degradation; it’s a fundamental change in the physical state of the material inside your pump.
| Original Liquid | Dried Residue State | Potential Problem |
|---|---|---|
| Saline or Buffer | Hard, Abrasive Salt Crystals | Scratches valves, tears diaphragm |
| Pigment-Based Ink | Solid, Cement-like Blockage | Completely clogs flow path |
| Protein Solution | Gummy, Sticky Biofilm | Fouls surfaces, harbors bacteria |
How Do These Clogs Destroy Pump Performance?
Your flow rate is dropping, but the motor sounds fine. Hidden blockages in the tiny valve seats and flow paths are choking your pump, causing system failure.
Even microscopic residue can obstruct the pump’s valves, preventing them from sealing properly. This leads to backflow, reduced suction, and a dramatic drop in the overall flow rate, compromising the entire fluidic system’s efficiency.

The mechanics of a diaphragm pump rely on perfect sealing. The diaphragm pulls back to create a vacuum, opening the inlet valve to draw liquid in. Then, it pushes forward to create pressure, closing the inlet valve and forcing the liquid out through the outlet valve. When residue prevents a valve from closing completely, the pump’s efficiency collapses. During the pressure stroke, liquid leaks back through the inlet. During the suction stroke, it fails to draw the full volume of new fluid. The result is a pump that is working hard but moving very little fluid.
What Kind of Permanent Damage Can Residue Cause?
You hear a strange noise, then the pump stops. Abrasive particles left behind have torn the diaphragm or scored the valve seats, causing catastrophic and irreversible failure.
Dried crystals or abrasive particles act like sandpaper inside the pump. They can physically tear the flexible diaphragm, scratch valve surfaces causing permanent leaks, and even strain the motor as it works harder against blockages.
While performance drops are frustrating, permanent damage is a far more expensive problem. Two key components are highly vulnerable:
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The Diaphragm: This flexible membrane is the heart of the pump. When abrasive residues like dried salt crystals are left inside, they create sharp points. As the diaphragm flexes against these points millions of times, it can suffer microscopic cuts that eventually lead to a full tear, causing total pump failure.
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The Valves and Valve Seats: The valves must create a perfect seal to work efficiently. Abrasive particles get dragged across the valve seat with every pump cycle. This action physically scratches and scores the sealing surfaces. Even a single deep scratch can create a permanent leak path, meaning the pump’s performance is permanently crippled.
How Can Cross-Contamination Ruin Your Process Integrity?
Your lab results are inconsistent and you can’t find the source. The problem might be your pump, carrying over residue from the previous fluid and contaminating every new sample.
In analytical or medical applications, even trace amounts of a previous chemical can invalidate results. Prompt flushing is the only way to ensure the purity of each sample and maintain the integrity of your process.
In many of the industries we serve at BODENFLO, fluid purity is non-negotiable. A diaphragm pump1 has a very small internal volume, so any leftover residue makes up a significant portion of the fluid path.
Think about these critical applications:
- Medical Diagnostics: A tiny amount of Reagent A left in the pump can cause a false positive when the pump is used to dispense Reagent B.
- Inkjet Printing: If a pump isn’t flushed when changing colors, the old pigment will contaminate the new ink, leading to incorrect colors and printhead clogs.
- Environmental Sampling: Residue from a highly concentrated water sample can contaminate the next, less concentrated sample, leading to dangerously inaccurate pollution readings.
Failing to clean the pump between fluids doesn’t just risk the pump; it risks the integrity of your entire operation.
Why Is Choosing the Right Cleaning Fluid So Crucial?
You decide to clean the pump, but grab the wrong solvent. The pump seems clean, but the solvent has silently attacked the diaphragm and seals, causing them to swell and fail prematurely.
Using an incompatible cleaning fluid is as bad as not cleaning at all. Solvents can cause the elastomer materials in diaphragms and valves (like EPDM or FKM) to swell, harden, or crack, leading to leaks and pump failure.

Every pump has "wetted materials2"—the parts that touch the fluid. At BODENFLO, these are typically high-grade elastomers chosen for their chemical resistance3. However, no single material is resistant to everything. Flushing an EPDM diaphragm pump with acetone, for example, is a recipe for disaster, as the EPDM will swell up and become useless.
Quick Compatibility Guide
| Pump Material | Generally Safe Solvents | SOLVENTS TO AVOID |
|---|---|---|
| EPDM | Water, Acetone, Ketones | Oils, Gasoline, Hydrocarbons |
| FKM (Viton®) | Oils, Fuels, Hydrocarbons | Ketones (e.g., Acetone), Esters |
| PTFE | Virtually all chemicals | N/A (Highly Inert) |
Always verify the compatibility of your cleaning fluid with your pump’s specific materials before you begin.
What Is the Correct Cleaning and Flushing Protocol?
You know you need to clean the pump, but what’s the right way to do it? Using the wrong cleaning fluid or method can be just as damaging as not cleaning at all.
The best practice is to flush the pump immediately after use with a compatible solvent that dissolves the residue. For most water-based fluids, deionized water is best. For others, a specific, verified cleaning solution is needed.
A proper cleaning protocol is simple but essential.
- Act Immediately: Do not let the fluid dry inside the pump. The best time to clean is right after the pumping task is complete.
- Choose the Right Solvent4: Based on the compatibility chart, choose a cleaning fluid that will dissolve the residue without harming the pump. When in doubt, contact your pump manufacturer.
- Flush Thoroughly: Run the cleaning fluid through the pump for at least one to two minutes. This ensures that the entire fluid path, including valve corners and hidden channels, is cleared of the previous liquid.
- Perform a Final Purge: If possible, run the pump dry for a few seconds or pass clean air through it to purge any remaining cleaning fluid. This is especially important if the cleaning solvent could interfere with your next process.
Conclusion
Promptly cleaning your diaphragm pump is not just maintenance. It is a critical procedure that protects your investment, ensures accuracy, and prevents unexpected system failure.
👉 Partner with BODENFLO for expert micro pump solutions. Contact us today at info@bodenpump.com
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Exploring diaphragm pumps will provide insights into their functionality and significance in ensuring fluid purity. ↩
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Understanding wetted materials is crucial for ensuring pump longevity and performance. ↩
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Exploring chemical resistance helps in selecting the right materials for specific applications. ↩
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Understanding the right solvent is crucial for effective cleaning without damaging your pump. ↩